Sensitivity Comparison of Two Commercial Interferon - Gamma 1 Release Assays in Pulmonary Tuberculosis
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چکیده
SENSITIVITY COMPARISON OF TWO COMMERCIAL INTERFERON-GAMMA 1 RELEASE ASSAYS IN PULMONARY TUBERCULOSIS 2 Cynthia B E Chee*, Suay H Gan, Kyi W KhinMar, Timothy M Barkham, 3 Chwee K Koh, Shen Liang, Yee T Wang 4 5 1 Singapore Tuberculosis Control Unit, Tan Tock Seng Hospital, Singapore 6 2 Dept of Pathology and Laboratory Medicine, Tan Tock Seng Hospital, 7 Singapore 8 3 Statistics Unit, Dean’s Office, Yong Loo Lin School of Medicine, National 9 University of Singapore 10 11
منابع مشابه
Comparison of sensitivities of two commercial gamma interferon release assays for pulmonary tuberculosis.
There are few head-to-head comparisons of the commercial gamma interferon release assays (GIRAs). We compared the performance of the T-SPOT.TB and QuantiFERON-TB Gold In-Tube (QFT-IT) assays in patients with culture-proven pulmonary tuberculosis. Blood was drawn for both assays within 14 days of starting antituberculosis treatment. The QFT-IT indeterminate rate was 3.5%; the T-SPOT.TB failure r...
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There is currently no 'gold standard' for diagnosis of latent tuberculosis infection (LTBI), and both the tuberculin skin test and interferon-gamma release assays (IGRAs) are used for diagnosis; the latter have a higher sensitivity than tuberculin skin tests for diagnosis of LTBI in HIV-infected individuals with lower CD4 counts. No evidence base exists for selection of IGRA methodology to iden...
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تاریخ انتشار 2008